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Pre-existing canine anti-IgG antibodies: implications for immunotherapy, immunogenicity testing and immunoassay analysis

One of the most enigmatic features of humoral immunity is the prevalent presence of circulating autoantibodies against IgG. These autoantibodies consist of several subsets, including rheumatoid factors, anti-Fab/anti-F(ab′)(2)-autoantibodies, and anti-idiotypic antibodies. Anti-IgG autoantibodies ca...

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Detalles Bibliográficos
Autores principales: Bergman, Daniel, Bäckström, Camilla, Hansson-Hamlin, Helene, Larsson, Anders, Holst, Bodil Ström
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391631/
https://www.ncbi.nlm.nih.gov/pubmed/32728049
http://dx.doi.org/10.1038/s41598-020-69618-3