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RADAR: annotation and prioritization of variants in the post-transcriptional regulome of RNA-binding proteins

RNA-binding proteins (RBPs) play key roles in post-transcriptional regulation and disease. Their binding sites cover more of the genome than coding exons; nevertheless, most noncoding variant prioritization methods only focus on transcriptional regulation. Here, we integrate the portfolio of ENCODE-...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Liu, Jason, Lee, Donghoon, Feng, Jo-Jo, Lochovsky, Lucas, Lou, Shaoke, Rutenberg-Schoenberg, Michael, Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391703/
https://www.ncbi.nlm.nih.gov/pubmed/32727537
http://dx.doi.org/10.1186/s13059-020-01979-4