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RADAR: annotation and prioritization of variants in the post-transcriptional regulome of RNA-binding proteins
RNA-binding proteins (RBPs) play key roles in post-transcriptional regulation and disease. Their binding sites cover more of the genome than coding exons; nevertheless, most noncoding variant prioritization methods only focus on transcriptional regulation. Here, we integrate the portfolio of ENCODE-...
Autores principales: | Zhang, Jing, Liu, Jason, Lee, Donghoon, Feng, Jo-Jo, Lochovsky, Lucas, Lou, Shaoke, Rutenberg-Schoenberg, Michael, Gerstein, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391703/ https://www.ncbi.nlm.nih.gov/pubmed/32727537 http://dx.doi.org/10.1186/s13059-020-01979-4 |
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