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Machine-learning approach expands the repertoire of anti-CRISPR protein families

The CRISPR-Cas are adaptive bacterial and archaeal immunity systems that have been harnessed for the development of powerful genome editing and engineering tools. In the incessant host-parasite arms race, viruses evolved multiple anti-defense mechanisms including diverse anti-CRISPR proteins (Acrs)...

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Detalles Bibliográficos
Autores principales: Gussow, Ayal B., Park, Allyson E., Borges, Adair L., Shmakov, Sergey A., Makarova, Kira S., Wolf, Yuri I., Bondy-Denomy, Joseph, Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391736/
https://www.ncbi.nlm.nih.gov/pubmed/32728052
http://dx.doi.org/10.1038/s41467-020-17652-0