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Machine-learning approach expands the repertoire of anti-CRISPR protein families
The CRISPR-Cas are adaptive bacterial and archaeal immunity systems that have been harnessed for the development of powerful genome editing and engineering tools. In the incessant host-parasite arms race, viruses evolved multiple anti-defense mechanisms including diverse anti-CRISPR proteins (Acrs)...
Autores principales: | Gussow, Ayal B., Park, Allyson E., Borges, Adair L., Shmakov, Sergey A., Makarova, Kira S., Wolf, Yuri I., Bondy-Denomy, Joseph, Koonin, Eugene V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391736/ https://www.ncbi.nlm.nih.gov/pubmed/32728052 http://dx.doi.org/10.1038/s41467-020-17652-0 |
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