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CD122-targetted IL-2 signals cause acute and selective apoptosis of B cells in Peyer’s Patches
Interleukin-2 (IL-2) has both pro- and anti-inflammatory properties that have been harnessed clinically and that are used experimentally to modulate leukocyte subsets in vivo. In mice, the bioavailability and half-life of IL-2 in vivo can be increased by complexing recombinant IL-2 with different cl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391758/ https://www.ncbi.nlm.nih.gov/pubmed/32728053 http://dx.doi.org/10.1038/s41598-020-69632-5 |