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PTEN suppresses epithelial–mesenchymal transition and cancer stem cell activity by downregulating Abi1

The epithelial–mesenchymal transition (EMT) is an embryonic program frequently reactivated during cancer progression and is implicated in cancer invasion and metastasis. Cancer cells can also acquire stem cell properties to self-renew and give rise to new tumors through the EMT. Inactivation of the...

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Detalles Bibliográficos
Autores principales: Qi, Yanmei, Liu, Jie, Chao, Joshua, Scheuerman, Mark P., Rahimi, Saum A., Lee, Leonard Y., Li, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391766/
https://www.ncbi.nlm.nih.gov/pubmed/32728066
http://dx.doi.org/10.1038/s41598-020-69698-1