Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids

Brain organoids are promising tools for disease modeling and drug development. For proper neuronal network formation excitatory and inhibitory neurons as well as glia need to co-develop. Here, we report the directed self-organization of human induced pluripotent stem cells in a collagen hydrogel tow...

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Detalles Bibliográficos
Autores principales: Zafeiriou, Maria-Patapia, Bao, Guobin, Hudson, James, Halder, Rashi, Blenkle, Alica, Schreiber, Marie-Kristin, Fischer, Andre, Schild, Detlev, Zimmermann, Wolfram-Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391775/
https://www.ncbi.nlm.nih.gov/pubmed/32728089
http://dx.doi.org/10.1038/s41467-020-17521-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391775/
https://www.ncbi.nlm.nih.gov/pubmed/32728089
http://dx.doi.org/10.1038/s41467-020-17521-w

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