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Unveiling functional heterogeneity in breast cancer multicellular tumor spheroids through single-cell RNA-seq
Heterogeneity is an intrinsic characteristic of cancer. Even in isogenic tumors, cell populations exhibit differential cellular programs that overall supply malignancy and decrease treatment efficiency. In this study, we investigated the functional relationship among cell subtypes and how this inter...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391783/ https://www.ncbi.nlm.nih.gov/pubmed/32728097 http://dx.doi.org/10.1038/s41598-020-69026-7 |