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Unveiling functional heterogeneity in breast cancer multicellular tumor spheroids through single-cell RNA-seq

Heterogeneity is an intrinsic characteristic of cancer. Even in isogenic tumors, cell populations exhibit differential cellular programs that overall supply malignancy and decrease treatment efficiency. In this study, we investigated the functional relationship among cell subtypes and how this inter...

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Detalles Bibliográficos
Autores principales: Muciño-Olmos, Erick Andrés, Vázquez-Jiménez, Aarón, Avila-Ponce de León, Ugo, Matadamas-Guzman, Meztli, Maldonado, Vilma, López-Santaella, Tayde, Hernández-Hernández, Abrahan, Resendis-Antonio, Osbaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391783/
https://www.ncbi.nlm.nih.gov/pubmed/32728097
http://dx.doi.org/10.1038/s41598-020-69026-7