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A Darwinian and Physical Look at Stem Cell Biology Helps Understanding the Role of Stochasticity in Development

Single-cell analysis allows biologists to gain huge insight into cell differentiation and tissue structuration. Randomness of differentiation, both in vitro and in vivo, of pluripotent (multipotent) stem cells is now demonstrated to be mainly based on stochastic gene expression. Nevertheless, it rem...

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Detalles Bibliográficos
Autores principales: Capp, Jean-Pascal, Laforge, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391792/
https://www.ncbi.nlm.nih.gov/pubmed/32793600
http://dx.doi.org/10.3389/fcell.2020.00659