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A Darwinian and Physical Look at Stem Cell Biology Helps Understanding the Role of Stochasticity in Development
Single-cell analysis allows biologists to gain huge insight into cell differentiation and tissue structuration. Randomness of differentiation, both in vitro and in vivo, of pluripotent (multipotent) stem cells is now demonstrated to be mainly based on stochastic gene expression. Nevertheless, it rem...
Autores principales: | Capp, Jean-Pascal, Laforge, Bertrand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391792/ https://www.ncbi.nlm.nih.gov/pubmed/32793600 http://dx.doi.org/10.3389/fcell.2020.00659 |
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