Cargando…

Glycerol-3-phosphate Acyltransferase1 Is a Model-Agnostic Node in Nonalcoholic Fatty Liver Disease: Implications for Drug Development and Precision Medicine

[Image: see text] Left untreated nonalcoholic fatty liver disease (NAFLD) can progress to nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma. The observed failure of clinical trials in NASH may suggest that current model systems do not fully recapitulate human dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Kimberly, Pellicano, Anthony J., Jiang, Kai, Prakash, Natalia, Li, Jingsong, Bhutkar, Shraddha, Hu, Zhijian, Ali, Quaisar, Goldberg, Itzhak D., Narayan, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391940/
https://www.ncbi.nlm.nih.gov/pubmed/32743224
http://dx.doi.org/10.1021/acsomega.0c02350