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Increased intracellular Cl(-) concentration improves airway epithelial migration by activating the RhoA/ROCK Pathway

In the airway, Cl(-) is the most abundant anion and is critically involved in transepithelial transport. The correlation of the abnormal expression and activation of chloride channels (CLCs), such as cystic fibrosis transmembrane conductance regulators (CFTRs), anoctamin-1, and CLC-2, with cell migr...

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Detalles Bibliográficos
Autores principales: Huang, Wenjie, Tan, Meiling, Wang, Yue, Liu, Lei, Pan, Yan, Li, Jingjing, Ouyang, Mingxing, Long, Chunjiao, Qu, Xiangping, Liu, Huijun, Liu, Chi, Wang, Jia, Deng, Linhong, Xiang, Yang, Qin, Xiaoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392015/
https://www.ncbi.nlm.nih.gov/pubmed/32754261
http://dx.doi.org/10.7150/thno.46002