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LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription

Sorafenib resistance is a major obstacle to the treatment of advanced hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) are multifunctional regulators of gene expression with profound impact for human disease. Therefore, better understanding of the biological mechanisms of abnormally expressed miRN...

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Detalles Bibliográficos
Autores principales: Lin, Zhongjie, Xia, Shunjie, Liang, Yuelong, Ji, Lin, Pan, Yu, Jiang, Shi, Wan, Zhe, Tao, Liye, Chen, Jiang, Lin, Chengping, Liang, Xiao, Xu, Junjie, Cai, Xiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392029/
https://www.ncbi.nlm.nih.gov/pubmed/32754282
http://dx.doi.org/10.7150/thno.45158