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The chemokine receptor antagonist cenicriviroc inhibits the replication of SARS-CoV-2 in vitro

Cenicriviroc (CVC) is a small-molecule chemokine receptor antagonist with highly potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity through antagonizing C–C chemokine receptor type 5 (CCR5) as a coreceptor of HIV-1. CVC also strongly antagonizes C–C chemokine receptor typ...

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Detalles Bibliográficos
Autores principales: Okamoto, Mika, Toyama, Masaaki, Baba, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392080/
https://www.ncbi.nlm.nih.gov/pubmed/32739404
http://dx.doi.org/10.1016/j.antiviral.2020.104902