A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice

SARS-CoV-2 infection has emerged as a serious global pandemic. Because of the high transmissibility of the virus and the high rate of morbidity and mortality associated with COVID-19, developing effective and safe vaccines is a top research priority. Here, we provide a detailed evaluation of the imm...

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Detalles Bibliográficos
Autores principales: Laczkó, Dorottya, Hogan, Michael J., Toulmin, Sushila A., Hicks, Philip, Lederer, Katlyn, Gaudette, Brian T., Castaño, Diana, Amanat, Fatima, Muramatsu, Hiromi, Oguin, Thomas H., Ojha, Amrita, Zhang, Lizhou, Mu, Zekun, Parks, Robert, Manzoni, Tomaz B., Roper, Brianne, Strohmeier, Shirin, Tombácz, István, Arwood, Leslee, Nachbagauer, Raffael, Karikó, Katalin, Greenhouse, Jack, Pessaint, Laurent, Porto, Maciel, Putman-Taylor, Tammy, Strasbaugh, Amanda, Campbell, Tracey-Ann, Lin, Paulo J.C., Tam, Ying K., Sempowski, Gregory D., Farzan, Michael, Choe, Hyeryun, Saunders, Kevin O., Haynes, Barton F., Andersen, Hanne, Eisenlohr, Laurence C., Weissman, Drew, Krammer, Florian, Bates, Paul, Allman, David, Locci, Michela, Pardi, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392193/
https://www.ncbi.nlm.nih.gov/pubmed/32783919
http://dx.doi.org/10.1016/j.immuni.2020.07.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392193/
https://www.ncbi.nlm.nih.gov/pubmed/32783919
http://dx.doi.org/10.1016/j.immuni.2020.07.019

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