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The conventional isoproterenol-induced heart failure model does not consistently mimic the diaphragmatic dysfunction observed in patients

Heart failure (HF) impairs diaphragm function. Animal models realistically mimicking HF should feature both the cardiac alterations and the diaphragmatic dysfunction characterizing this disease. The isoproterenol-induced HF model is widely used, but whether it presents diaphragmatic dysfunction is u...

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Detalles Bibliográficos
Autores principales: Cabrera-Aguilera, Ignacio, Falcones, Bryan, Calvo-Fernández, Alicia, Benito, Begoña, Barreiro, Esther, Gea, Joaquim, Farré, Ramon, Almendros, Isaac, Farré, Núria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392250/
https://www.ncbi.nlm.nih.gov/pubmed/32730329
http://dx.doi.org/10.1371/journal.pone.0236923