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Inhibition of ALAS1 activity exerts anti-tumour effects on colorectal cancer in vitro

BACKGROUND/AIMS: Colorectal cancer (CRC) is the third most common malignant tumour worldwide and the second leading cause of cancer-related deaths. Commonly, 5'-aminolevulinic acid synthase1 (ALAS1) is the rate-limiting enzyme for haem biosynthesis. Recent studies have shown that ALAS1 is invol...

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Detalles Bibliográficos
Autores principales: Zhao, Yalei, Zhang, Xiaoyun, Liu, Yabin, Ma, Yiping, Kong, Pong, Bai, Tianliang, Han, Mei, Li, Binghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392291/
https://www.ncbi.nlm.nih.gov/pubmed/32270771
http://dx.doi.org/10.4103/sjg.SJG_477_19