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Increased hepatic and circulating chemokine and osteopontin expression occurs early in human NAFLD development

BACKGROUND & AIMS: Non-alcoholic steatohepatitis (NASH), a subtype of non-alcoholic fatty liver disease (NAFLD) that can lead to fibrosis, cirrhosis, and hepatocellular carcinoma, is characterized by hepatic inflammation. Despite evolving therapies aimed to ameliorate inflammation in NASH, the t...

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Detalles Bibliográficos
Autores principales: Kriss, Michael, Golden-Mason, Lucy, Kaplan, Jeffrey, Mirshahi, Faridoddin, Setiawan, V. Wendy, Sanyal, Arun J., Rosen, Hugo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392333/
https://www.ncbi.nlm.nih.gov/pubmed/32730345
http://dx.doi.org/10.1371/journal.pone.0236353