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Role for Metallothionein-3 in the Resistance of Human U87 Glioblastoma Cells to Temozolomide

[Image: see text] Metallothioneins (MTs) are metal-binding proteins that are overexpressed in various human cancers and are thought to be associated with resistance to cytotoxic drugs. The knowledge on MT expression, regulation, and function in human gliomas is limited. We found that MT3 mRNA was hi...

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Detalles Bibliográficos
Autores principales: Santangelo, Rosa, Rizzarelli, Enrico, Copani, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392386/
https://www.ncbi.nlm.nih.gov/pubmed/32743161
http://dx.doi.org/10.1021/acsomega.9b04483