Peroxiredoxin promotes longevity and H(2)O(2)-resistance in yeast through redox-modulation of protein kinase A

Peroxiredoxins are H(2)O(2) scavenging enzymes that also carry out H(2)O(2) signaling and chaperone functions. In yeast, the major cytosolic peroxiredoxin, Tsa1 is required for both promoting resistance to H(2)O(2) and extending lifespan upon caloric restriction. We show here that Tsa1 effects both...

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Detalles Bibliográficos
Autores principales: Roger, Friederike, Picazo, Cecilia, Reiter, Wolfgang, Libiad, Marouane, Asami, Chikako, Hanzén, Sarah, Gao, Chunxia, Lagniel, Gilles, Welkenhuysen, Niek, Labarre, Jean, Nyström, Thomas, Grøtli, Morten, Hartl, Markus, Toledano, Michel B, Molin, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392609/
https://www.ncbi.nlm.nih.gov/pubmed/32662770
http://dx.doi.org/10.7554/eLife.60346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392609/
https://www.ncbi.nlm.nih.gov/pubmed/32662770
http://dx.doi.org/10.7554/eLife.60346

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