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Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D(3) in breast cancer

1,25-Dihydroxyvitamin D(3) (1,25D3) induces growth arrest and apoptosis in breast cancer cells in vivo and in vitro, however the exact mechanisms are unclear. Although the vitamin D receptor (VDR), a ligand dependent transcription factor, is required for growth regulation by vitamin D, the specific...

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Detalles Bibliográficos
Autores principales: Narvaez, Carmen J., LaPorta, Erika, Robilotto, Samantha, Liang, Jennifer, Welsh, JoEllen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392624/
https://www.ncbi.nlm.nih.gov/pubmed/32774770
http://dx.doi.org/10.18632/oncotarget.27587