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cGAS-STING pathway in oncogenesis and cancer therapeutics

The host innate immunity offers the first line of defense against infection. However, recent evidence shows that the host innate immunity is also critical in sensing the presence of cytoplasmic DNA derived from genomic instability events, such as DNA damage and defective cell cycle progression. This...

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Detalles Bibliográficos
Autores principales: Hoong, Brandon Yi Da, Gan, Yunn Hwen, Liu, Haiyan, Chen, Ee Sin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392626/
https://www.ncbi.nlm.nih.gov/pubmed/32774773
http://dx.doi.org/10.18632/oncotarget.27673