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Splicing-accessible coding 3′UTRs control protein stability and interaction networks

BACKGROUND: 3′-Untranslated regions (3′UTRs) play crucial roles in mRNA metabolism, such as by controlling mRNA stability, translation efficiency, and localization. Intriguingly, in some genes the 3′UTR is longer than their coding regions, pointing to additional, unknown functions. Here, we describe...

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Detalles Bibliográficos
Autores principales: Preussner, Marco, Gao, Qingsong, Morrison, Eliot, Herdt, Olga, Finkernagel, Florian, Schumann, Michael, Krause, Eberhard, Freund, Christian, Chen, Wei, Heyd, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392665/
https://www.ncbi.nlm.nih.gov/pubmed/32727563
http://dx.doi.org/10.1186/s13059-020-02102-3