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Nrf2 promotes esophageal squamous cell carcinoma (ESCC) resistance to radiotherapy through the CaMKIIα-associated activation of autophagy

BACKGROUND: NF-E2-related factor 2 (Nrf2) is involved in the radiation resistance of esophageal squamous cell carcinoma (ESCC), but the underlying molecular mechanism is unclear. The purpose of our study was to explore the role of Nrf2 in the radiation resistance of ESCC and the potential molecular...

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Detalles Bibliográficos
Autores principales: Xia, Di, Zhang, Xiao-Ran, Ma, Yan-Li, Zhao, Zhi-Jun, Zhao, Ren, Wang, Yan-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392680/
https://www.ncbi.nlm.nih.gov/pubmed/32760495
http://dx.doi.org/10.1186/s13578-020-00456-6