Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model

BACKGROUND: Neural circuits are initially assembled during development when neurons synapse with potential partners and later refined as appropriate connections stabilize into mature synapses while inappropriate contacts are eliminated. Disruptions to this synaptogenic process impair connectivity op...

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Detalles Bibliográficos
Autores principales: Kennedy, Tyler, Rinker, David, Broadie, Kendal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392683/
https://www.ncbi.nlm.nih.gov/pubmed/32731855
http://dx.doi.org/10.1186/s12915-020-00817-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392683/
https://www.ncbi.nlm.nih.gov/pubmed/32731855
http://dx.doi.org/10.1186/s12915-020-00817-0

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