Cargando…
Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model
BACKGROUND: Neural circuits are initially assembled during development when neurons synapse with potential partners and later refined as appropriate connections stabilize into mature synapses while inappropriate contacts are eliminated. Disruptions to this synaptogenic process impair connectivity op...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392683/ https://www.ncbi.nlm.nih.gov/pubmed/32731855 http://dx.doi.org/10.1186/s12915-020-00817-0 |