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Evaluating the effect of TLR4-overexpressing on the transcriptome profile in ovine peripheral blood mononuclear cells

BACKGROUND: Toll-like receptor 4 (TLR4) plays an important role in the elimination of Gram-negative bacteria infections and the initiation of antiinflammatory response. Using the technology of pronuclear microinjection, genetically modified (GM) sheep with TLR4 overexpression were generated. Previou...

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Detalles Bibliográficos
Autores principales: Guo, Xiaofei, Zhang, Jinlong, Li, Yao, Yang, Jing, Li, Yihai, Dong, Chunxiao, Liu, Guoshi, Lian, Zhengxing, Zhang, Xiaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392728/
https://www.ncbi.nlm.nih.gov/pubmed/32760682
http://dx.doi.org/10.1186/s40709-020-00124-3