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Evaluating the effect of TLR4-overexpressing on the transcriptome profile in ovine peripheral blood mononuclear cells

BACKGROUND: Toll-like receptor 4 (TLR4) plays an important role in the elimination of Gram-negative bacteria infections and the initiation of antiinflammatory response. Using the technology of pronuclear microinjection, genetically modified (GM) sheep with TLR4 overexpression were generated. Previou...

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Detalles Bibliográficos
Autores principales:	Guo, Xiaofei, Zhang, Jinlong, Li, Yao, Yang, Jing, Li, Yihai, Dong, Chunxiao, Liu, Guoshi, Lian, Zhengxing, Zhang, Xiaosheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392728/ https://www.ncbi.nlm.nih.gov/pubmed/32760682 http://dx.doi.org/10.1186/s40709-020-00124-3

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