Toll-like receptor dual-acting agonists are potent inducers of PBMC-produced cytokines that inhibit hepatitis B virus production in primary human hepatocytes

Recombinant interferon-α (IFN-α) treatment functionally cures chronic hepatitis B virus (HBV) infection in some individuals and suppresses virus replication in hepatocytes infected in vitro. We studied the antiviral effect of conditioned media (CM) from peripheral blood mononuclear cells (PBMCs) sti...

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Detalles Bibliográficos
Autores principales: Janovec, Vaclav, Hodek, Jan, Clarova, Kamila, Hofman, Tomas, Dostalik, Pavel, Fronek, Jiri, Chlupac, Jaroslav, Chaperot, Laurence, Durand, Sarah, Baumert, Thomas F., Pichova, Iva, Lubyova, Barbora, Hirsch, Ivan, Weber, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392756/
https://www.ncbi.nlm.nih.gov/pubmed/32728070
http://dx.doi.org/10.1038/s41598-020-69614-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392756/
https://www.ncbi.nlm.nih.gov/pubmed/32728070
http://dx.doi.org/10.1038/s41598-020-69614-7

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