Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles

BACKGROUND: Endosomal trafficking and amyloidogenic cleavage of amyloid precursor protein (APP) is believed to play a role in the neurodegeneration observed in Alzheimer’s disease (AD). Recent evidence has suggested that packaging and secretion of APP and its amyloidogenic cleaved products into smal...

Descripción completa

Detalles Bibliográficos
Autores principales: Cone, Allaura S., Hurwitz, Stephanie N., Lee, Gloria S., Yuan, Xuegang, Zhou, Yi, Li, Yan, Meckes, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392838/
https://www.ncbi.nlm.nih.gov/pubmed/32731849
http://dx.doi.org/10.1186/s12860-020-00302-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392838/
https://www.ncbi.nlm.nih.gov/pubmed/32731849
http://dx.doi.org/10.1186/s12860-020-00302-0

Ejemplares similares