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Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles

BACKGROUND: Endosomal trafficking and amyloidogenic cleavage of amyloid precursor protein (APP) is believed to play a role in the neurodegeneration observed in Alzheimer’s disease (AD). Recent evidence has suggested that packaging and secretion of APP and its amyloidogenic cleaved products into smal...

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Detalles Bibliográficos
Autores principales:	Cone, Allaura S., Hurwitz, Stephanie N., Lee, Gloria S., Yuan, Xuegang, Zhou, Yi, Li, Yan, Meckes, David G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392838/ https://www.ncbi.nlm.nih.gov/pubmed/32731849 http://dx.doi.org/10.1186/s12860-020-00302-0

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