Design, Synthesis, Molecular Modeling Study and Biological Evaluation of New N'-Arylidene-pyrido [2,3-d]pyrimidine-5-carbohydrazide Derivatives as Anti-HIV-1 Agents

In an attempt to identify potential new agents that are active against HIV-1, a series of novel pyridopyrimidine-5-carbohydrazide derivatives featuring a substituted benzylidene fragment were designed and synthesized based on the general pharmacophore of HIV-1 integrase inhibitors. The cytotoxicity...

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Detalles Bibliográficos
Autores principales: Ebrahimzadeh, Elnaz, Tabatabai, Seyyed Abbas, Vahabpour, Rouhollah, Hajimahdi, Zahra, Zarghi, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393058/
https://www.ncbi.nlm.nih.gov/pubmed/32802103
http://dx.doi.org/10.22037/ijpr.2019.112198.13597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393058/
https://www.ncbi.nlm.nih.gov/pubmed/32802103
http://dx.doi.org/10.22037/ijpr.2019.112198.13597

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