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CDK Blockade Using AT7519 Suppresses Acute Myeloid Leukemia Cell Survival through the Inhibition of Autophagy and Intensifies the Anti-leukemic Effect of Arsenic Trioxide

The strong storyline behind the critical role of cyclin-dependent kinase (CDK) inhibitor proteins in natural defense against malignant transformation not only represents a heroic perspective for these proteins, but also provides a bright future for the application of small molecule inhibitors of CDK...

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Detalles Bibliográficos
Autores principales: Zabihi, Mitra, Safaroghli-Azar, Ava, Gharehbaghian, Ahmad, Allahbakhshian Farsani, Mehdi, Bashash, Davood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393062/
https://www.ncbi.nlm.nih.gov/pubmed/32802093
http://dx.doi.org/10.22037/ijpr.2019.112560.13827