CFTR Modulators Dampen Aspergillus-Induced Reactive Oxygen Species Production by Cystic Fibrosis Phagocytes

Excessive inflammation by phagocytes during Aspergillus fumigatus infection is thought to promote lung function decline in CF patients. CFTR modulators have been shown to reduce A. fumigatus colonization in vivo, however, their antifungal and anti-inflammatory mechanisms are unclear. Other treatment...

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Detalles Bibliográficos
Autores principales: Currie, Alexander J., Main, Ellen T., Wilson, Heather M., Armstrong-James, Darius, Warris, Adilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393064/
https://www.ncbi.nlm.nih.gov/pubmed/32793514
http://dx.doi.org/10.3389/fcimb.2020.00372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393064/
https://www.ncbi.nlm.nih.gov/pubmed/32793514
http://dx.doi.org/10.3389/fcimb.2020.00372

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