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Strategies to enable large-scale proteomics for reproducible research

Reproducible research is the bedrock of experimental science. To enable the deployment of large-scale proteomics, we assess the reproducibility of mass spectrometry (MS) over time and across instruments and develop computational methods for improving quantitative accuracy. We perform 1560 data indep...

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Detalles Bibliográficos
Autores principales: Poulos, Rebecca C., Hains, Peter G., Shah, Rohan, Lucas, Natasha, Xavier, Dylan, Manda, Srikanth S., Anees, Asim, Koh, Jennifer M. S., Mahboob, Sadia, Wittman, Max, Williams, Steven G., Sykes, Erin K., Hecker, Michael, Dausmann, Michael, Wouters, Merridee A., Ashman, Keith, Yang, Jean, Wild, Peter J., deFazio, Anna, Balleine, Rosemary L., Tully, Brett, Aebersold, Ruedi, Speed, Terence P., Liu, Yansheng, Reddel, Roger R., Robinson, Phillip J., Zhong, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393074/
https://www.ncbi.nlm.nih.gov/pubmed/32732981
http://dx.doi.org/10.1038/s41467-020-17641-3