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Circ-GLI1 promotes metastasis in melanoma through interacting with p70S6K2 to activate Hedgehog/GLI1 and Wnt/β-catenin pathways and upregulate Cyr61

Circular RNAs (circRNAs) are emerging regulators in the development of human cancers. However, the role of circRNAs in melanoma is poorly understood. Microarray analysis and qRT-PCR was applied to screen out circRNAs that were differentially expressed in melanoma cells compared to normal cells. Curr...

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Detalles Bibliográficos
Autores principales: Chen, Jun, Zhou, Xiaobo, Yang, Jie, Sun, Qilin, Liu, Yang, Li, Ningli, Zhang, Zhen, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393080/
https://www.ncbi.nlm.nih.gov/pubmed/32732916
http://dx.doi.org/10.1038/s41419-020-02799-x