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Circ-GLI1 promotes metastasis in melanoma through interacting with p70S6K2 to activate Hedgehog/GLI1 and Wnt/β-catenin pathways and upregulate Cyr61
Circular RNAs (circRNAs) are emerging regulators in the development of human cancers. However, the role of circRNAs in melanoma is poorly understood. Microarray analysis and qRT-PCR was applied to screen out circRNAs that were differentially expressed in melanoma cells compared to normal cells. Curr...
Autores principales: | Chen, Jun, Zhou, Xiaobo, Yang, Jie, Sun, Qilin, Liu, Yang, Li, Ningli, Zhang, Zhen, Xu, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393080/ https://www.ncbi.nlm.nih.gov/pubmed/32732916 http://dx.doi.org/10.1038/s41419-020-02799-x |
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