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Long-term administration of recombinant canstatin prevents adverse cardiac remodeling after myocardial infarction

Myocardial infarction (MI) still remains a leading cause of mortality throughout the world. An adverse cardiac remodeling, such as hypertrophy and fibrosis, in non-infarcted area leads to uncompensated heart failure with cardiac dysfunction. We previously demonstrated that canstatin, a C-terminus fr...

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Detalles Bibliográficos
Autores principales: Sugiyama, Akira, Ito, Rumi, Okada, Muneyoshi, Yamawaki, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393096/
https://www.ncbi.nlm.nih.gov/pubmed/32732948
http://dx.doi.org/10.1038/s41598-020-69736-y