Metabolomic and transcriptomic signatures of prenatal excessive methionine support nature rather than nurture in schizophrenia pathogenesis

The imbalance of prenatal micronutrients may perturb one-carbon (C1) metabolism and increase the risk for neuropsychiatric disorders. Prenatal excessive methionine (MET) produces in mice behavioral phenotypes reminiscent of human schizophrenia. Whether in-utero programming or early life caregiving m...

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Detalles Bibliográficos
Autores principales: Chen, Siwei, Alhassen, Wedad, Yoshimura, Ryan, De Silva, Angele, Abbott, Geoffrey W., Baldi, Pierre, Alachkar, Amal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393105/
https://www.ncbi.nlm.nih.gov/pubmed/32732995
http://dx.doi.org/10.1038/s42003-020-01124-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393105/
https://www.ncbi.nlm.nih.gov/pubmed/32732995
http://dx.doi.org/10.1038/s42003-020-01124-8

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