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The SecA motor generates mechanical force during protein translocation

The Sec translocon moves proteins across lipid bilayers in all cells. The Sec channel enables passage of unfolded proteins through the bacterial plasma membrane, driven by the cytosolic ATPase SecA. Whether SecA generates mechanical force to overcome barriers to translocation posed by structured sub...

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Detalles Bibliográficos
Autores principales: Gupta, Riti, Toptygin, Dmitri, Kaiser, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393111/
https://www.ncbi.nlm.nih.gov/pubmed/32732903
http://dx.doi.org/10.1038/s41467-020-17561-2