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The SecA motor generates mechanical force during protein translocation
The Sec translocon moves proteins across lipid bilayers in all cells. The Sec channel enables passage of unfolded proteins through the bacterial plasma membrane, driven by the cytosolic ATPase SecA. Whether SecA generates mechanical force to overcome barriers to translocation posed by structured sub...
Autores principales: | Gupta, Riti, Toptygin, Dmitri, Kaiser, Christian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393111/ https://www.ncbi.nlm.nih.gov/pubmed/32732903 http://dx.doi.org/10.1038/s41467-020-17561-2 |
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