Isoform-specific characterization of class I histone deacetylases and their therapeutic modulation in pulmonary hypertension

Pharmacological modulation of class I histone deacetylases (HDAC) has been evaluated as a therapeutic strategy for pulmonary hypertension (PH) in experimental models of PH. However, information of their expression, regulation and transcriptional targets in human PH and the therapeutic potential of i...

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Detalles Bibliográficos
Autores principales: Chelladurai, Prakash, Dabral, Swati, Basineni, Sobha Rani, Chen, Chien-Nien, Schmoranzer, Mario, Bender, Nina, Feld, Christine, Nötzold, René Reiner, Dobreva, Gergana, Wilhelm, Jochen, Jungblut, Benno, Zhao, Lan, Bauer, Uta-Maria, Seeger, Werner, Pullamsetti, Soni Savai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393135/
https://www.ncbi.nlm.nih.gov/pubmed/32733053
http://dx.doi.org/10.1038/s41598-020-69737-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393135/
https://www.ncbi.nlm.nih.gov/pubmed/32733053
http://dx.doi.org/10.1038/s41598-020-69737-x

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