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Improving the diversity of captured full-length isoforms using a normalized single-molecule RNA-sequencing method

Human genes form a large variety of isoforms after transcription, encoding distinct transcripts to exert different functions. Single-molecule RNA sequencing facilitates accurate identification of the isoforms by extending nucleotide read length significantly. However, the gene or isoform diversity i...

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Detalles Bibliográficos
Autores principales: Hu, Yueming, Shu, Xing-Sheng, Yu, Jiaxian, Sun, Ming-an, Chen, Zewei, Liu, Xianming, Fang, Qiongfang, Zhang, Wei, Hui, Xinjie, Ying, Ying, Fu, Li, Lu, Desheng, Kumar, Rakesh, Wang, Yejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393167/
https://www.ncbi.nlm.nih.gov/pubmed/32732980
http://dx.doi.org/10.1038/s42003-020-01125-7