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Improving the diversity of captured full-length isoforms using a normalized single-molecule RNA-sequencing method
Human genes form a large variety of isoforms after transcription, encoding distinct transcripts to exert different functions. Single-molecule RNA sequencing facilitates accurate identification of the isoforms by extending nucleotide read length significantly. However, the gene or isoform diversity i...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393167/ https://www.ncbi.nlm.nih.gov/pubmed/32732980 http://dx.doi.org/10.1038/s42003-020-01125-7 |