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Identification of relevant genetic alterations in cancer using topological data analysis

Large-scale cancer genomic studies enable the systematic identification of mutations that lead to the genesis and progression of tumors, uncovering the underlying molecular mechanisms and potential therapies. While some such mutations are recurrently found in many tumors, many others exist solely wi...

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Detalles Bibliográficos
Autores principales: Rabadán, Raúl, Mohamedi, Yamina, Rubin, Udi, Chu, Tim, Alghalith, Adam N., Elliott, Oliver, Arnés, Luis, Cal, Santiago, Obaya, Álvaro J., Levine, Arnold J., Cámara, Pablo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393176/
https://www.ncbi.nlm.nih.gov/pubmed/32732999
http://dx.doi.org/10.1038/s41467-020-17659-7