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Fibroblast Growth Factor Receptor 4 Deficiency Mediates Airway Inflammation in the Adult Healthy Lung?

Fibroblast growth factor receptor (FGFR) 4 has been shown to mediate pro-inflammatory signaling in the liver and airway epithelium in chronic obstructive pulmonary disease. In past reports, FGFR4 knockout (Fgfr4(−/−)) mice did not show any lung phenotype developmentally or at birth, unless FGFR3 def...

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Detalles Bibliográficos
Autores principales: Easter, Molly, Garth, Jaleesa, Harris, Elex S., Shei, Ren-Jay, Helton, Eric S., Wei, Yuhua, Denson, Rebecca, Zaharias, Rennan, Rowe, Steven M., Geraghty, Patrick, Faul, Christian, Barnes, Jarrod W., Krick, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393220/
https://www.ncbi.nlm.nih.gov/pubmed/32793609
http://dx.doi.org/10.3389/fmed.2020.00317