PROTECT Trial: A cluster-randomized study with hydroxychloroquine versus observational support for prevention or early-phase treatment of Coronavirus disease (COVID-19): A structured summary of a study protocol for a randomized controlled trial

OBJECTIVES: Hydroxychloroquine has shown to have antiviral activity in vitro against coronaviruses, specifically SARS-CoV-2. It is believed to block virus infection by increasing endosomal pH required for virus cell fusion and glycosylation of viral surface proteins. In addition to its antiviral act...

Descripción completa

Detalles Bibliográficos
Autores principales: Nanni, Oriana, Viale, Pierluigi, Vertogen, Bernadette, Lilli, Claudia, Zingaretti, Chiara, Donati, Caterina, Masini, Carla, Monti, Manuela, Serra, Patrizia, Vespignani, Roberto, Grossi, Veruska, Biggeri, Annibale, Scarpi, Emanuela, Galardi, Francesca, Bertoni, Lucia, Colamartini, Americo, Falcini, Fabio, Altini, Mattia, Massa, Ilaria, Gaggeri, Raffaella, Martinelli, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393246/
https://www.ncbi.nlm.nih.gov/pubmed/32736597
http://dx.doi.org/10.1186/s13063-020-04527-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393246/
https://www.ncbi.nlm.nih.gov/pubmed/32736597
http://dx.doi.org/10.1186/s13063-020-04527-4

Ejemplares similares