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Encouraging Clinical Evolution of a Pediatric Patient With Relapsed Diffuse Midline Glioma Who Underwent WT1-Targeting Immunotherapy: A Case Report and Literature Review

Diffuse midline glioma (DMG) in children is a highly aggressive, malignant brain tumor that is fatal when relapsed. Wilms tumor 1 (WT1) is a high-priority antigen target for cancer immunotherapy. We hereby report on a pediatric patient who had DMG that regrew after chemoradiotherapy and underwent WT...

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Detalles Bibliográficos
Autores principales: Hashii, Yoshiko, Oka, Yoshihiro, Kagawa, Naoki, Hashimoto, Naoya, Saitou, Hiroyuki, Fukuya, Syogo, Kanegae, Mizuki, Ikejima, Sayaka, Oji, Yusuke, Ozono, Keiichi, Tsuboi, Akihiro, Sugiyama, Haruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393264/
https://www.ncbi.nlm.nih.gov/pubmed/32793489
http://dx.doi.org/10.3389/fonc.2020.01188