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Quality assessment tests for tumorigenicity of human iPS cell-derived cartilage

Articular cartilage damage does not heal spontaneously and causes joint dysfunction. The implantation of induced pluripotent stem cell (iPSC)-derived cartilage (iPS-Cart) is one candidate treatment to regenerate the damaged cartilage. However, concerns of tumorigenicity are associated with iPS-Cart,...

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Detalles Bibliográficos
Autores principales: Takei, Yoshiaki, Morioka, Miho, Yamashita, Akihiro, Kobayashi, Tomohito, Shima, Nobuyuki, Tsumaki, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393378/
https://www.ncbi.nlm.nih.gov/pubmed/32732907
http://dx.doi.org/10.1038/s41598-020-69641-4