Ready for Repair? Gene Editing Enters the Clinic for the Treatment of Human Disease

We present an overview of clinical trials involving gene editing using clustered interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9), transcription activator-like effector nucleases (TALENs), or zinc finger nucleases (ZFNs) and discuss the underlying mechanisms. In canc...

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Detalles Bibliográficos
Autores principales: Ernst, Martijn P.T., Broeders, Mike, Herrero-Hernandez, Pablo, Oussoren, Esmee, van der Ploeg, Ans T., Pijnappel, W.W.M. Pim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393410/
https://www.ncbi.nlm.nih.gov/pubmed/32775490
http://dx.doi.org/10.1016/j.omtm.2020.06.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393410/
https://www.ncbi.nlm.nih.gov/pubmed/32775490
http://dx.doi.org/10.1016/j.omtm.2020.06.022

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